The role of women in fisheries sector and their participation in marketing is not well recognized. Eventhough women play a significant role in the field of fish retail marketing, they are facing a lot of challenges in their day to day life. Hence, the study attempted to examine the constraints faced by women in retail fish marketing sector. The study has been undertaken in Thoothukudi region of Tamil Nadu. The sample size of the study was 50 which was selected by simple random sampling method. The primary data were collected from the respondents using survey schedule. The collected data was tabulated and analysed applying Rank Based Quotient Technique. The study revealed that the middlemen exploitation, uncertainty in price, inability to carry fish to longer distance, lack of hygienic condition to sell fish, competition from other retailers, non-availability of fish in marketing were the major marketing related constraints faced by them. Similarly, high debt and dowry along with little or no influence in decision making process, low literacy rate, lack of education and shortage of drinking water facilities were the major socio-economic constraints. Production incentives to those engaged in marketing, strengthening the fisheries cooperatives, lending amount with minimum interest are suggested to improve their condition to some extent. They should be made aware about the various schemes and policies implemented by the Government so that the exploitation by external forces can be minimised.