The present study deals with the efficacy of modified panchagavya for production of zooplankton in reference to water quality. The experiment was carried out with five different doses of liquid organic manure modified panchagavya at the different levels viz. 0.15 % (T1), 0.20 % (T2), 0.25 % (T3), 0.30 % (T4), 0.35% (T5), besides one control (T0) using fresh cow dung at the rate of 50g/ tank of 50 l. Each treatment was with three replicates. The experiment was conducted in a glass aquarium of 56 litre capacity for six weeks. The zooplankton production and water quality were observed at weekly intervals and some parameters like water temperature, pH and DO (dissolved oxygen) were observed every day. During the experimental period, the water quality parameters were found congenial for zooplankton growth. Range of water quality parameters were: water temperature: 23.39 - 23.53℃, pH: 7.4-8.5, Electrical conductivity (EC): 1.26-1.47 mS/cm, DO: 6.11- 6.92 mg/l, total alkalinity: 109-151.05 mg/l, total hardness: 770.68-962.83 mg/l, TDS: 806.40-942.93 mg/l, nitrate-nitrogen: 1.49-2.66 mg/l, orthophosphate: 0.36-0.68 mg/l. Significantly (p<0.05) higher plankton population and zooplankton biomass were found in T4 (748.43 No's/l & 17.12 g/tank). The trend of best dose of modified panchagavya based on zooplankton production (population and biomass) in descending order in the present study are T4 (0.30 %) > T3 (0.25 %) >T5 (0.35%) > T2 (0.20 %) > T1 (0.15 %) . The trend of dominant zooplankton categories observed by percent contribution in all treatments are Cladocerans (33%) followed by Copepods (30%), Nauplii (21%) and Rotifers (16%). Consequently, from the results obtained it can be concluded that the use of 0.30% modified panchagavya is most useful for zooplankton production to get good performance with aqua friendly effects on the rearing environment.