A study evaluating water quality and nutrient dynamics in inland saline water was carried out using biofloc technology with different C/N ratios employed to raise Litopenaeus vannamei juveniles. The ionic composition of the water prior to experiment initiation were analysed and fortified with Potassium Chloride (KCl) and Magnesium Chloride (MgCl2). The study was carried out for 60 days in FRP with no water exchange. The 18 FRP circular tanks (500L) with one control C (clear water) and five treatments (with different C/N ratios) T1 (10:1), T2 (15:1), T3 (20:1) and T4 (25:1) were filled with fortified 15 ppt inland ground saline waters. Input C/N ratios were calculated based on the carbon nitrogen contents of the feed and the carbon content of the Rice bran. The nitrogen content of feed estimated by the Kjeldahl method and accordingly each gram of feed, carbon source as Rice bran added into each treatment tank for maintain the C/N ratio. Salinity, temperature, Dissolved oxygen, pH, nutrients, Biofloc Volume and Total Suspended Solids were monitored. All biofloc units indicated reduction in alkalinity at 40th day except the treatment with highest (25:1) C/N ratio, pH and alkalinity was not significant different among various treatments. Dissolved Oxygen was found to be significantly decreasing with increasing C/N ratios. The least Dissolved Oxygen was recorded at higher C/N ratios of 20:1 and 25:1 at the end of experiment. The Total Ammonical Nitrogen (TAN) and NO2-N in C/N ratios 15:1 and 20:1 were found to have a significantly decreasing in trend after 20th and 18th day respectively. The NO3-N,PO43--P ,BVF and TSS in biofloc were shown an increasing trend in all the experiments. The present study elucidates the suitability of optimum C/N ratios in biofloc for maintaining the water quality to raise L. vannamei in inland ground saline water. The finding could help in reducing the environmental concern saline waste water discharge from the shrimp pond to the land.