4- [5- (3,4-Dimethoxyphenyl) -3- (4-bromophenyl) -4,5-dihydro-1H-pyrazol-1-yl] benzenesulfonamide (B8) compound was synthesized and rainbow trout juveniles were exposed to the B8 for 48 hours. Exposure doses were 0, 0.25, 0.5, 1 and 2.5 mg/L 1 ml of DMSO.
At the and of the experiments it was determined that 2.5 ppm B8 changed the critical swimming speed significantly (p<0.05). The effects of B8 on brain with respect to MDA Level ( nmol / ml) and AChE Activity (EU / mg) were significant (p<0.05) also.
It is suggested that B8 should be investigated further for possible usage in aquaculture industry to produce healthy fish.
Key words: MDA, AChE, Swimming speed, rainbow trout, pyrazoline, B8