At the University of Idaho, recent efforts have focused on the evaluation and selection of optimal diet formulations for burbot ( Lota lota maculosa) . Previous findings demonstrated that juvenile burbot perform well on marine-type commercial diets, whereas subadults grow equally well on a trout-like diet. As with many cultured fish species, utilizing plant-based proteins in aquafeed formulations is desirable to ultimately reduce the amount of required fishmeal . A 72 d feeding trial was conducted to characterize the growth performance and associated intestinal microbiota associated with feeding burbot diets containing fishmeal replacement with soybean meal (SBM) and dried distillers gains with solubles (DDGS) . As such, young-of the year burbot (8.2±0.1g; triplicate tanks ) were cultured in aerated flow-through tanks at 13C . With respect to dietary treatments, an Atlantic cod marine-type (fishmeal-based control; REF) diet was formulated to approximately 48% crude protein and 16% lipid and fishmeal protein content was replaced at 25% with inclusions of SBM and DDGS. In this trial, burbot were fed to apparent satiation to maximize feed intake and obtain accurate data metrics for consumption and conversion. Performance data collected at 36d and 72d were analyzed using ANOVA and post-hoc testing with Tukey's HSD ( priori=0.05). Growth results from the trial endpoint indicate comparable performance for the FM and SBM diets, while DDGS diet did not show favorable performance when compared to the SBM or FM diet. For feed conversion ratio (FCR; P=0.019), the burbot fed the REF diet showed the best conversion (0.80±0.01), which was better than the SBM (0.98±0.03) and DDGS (0.96±0 .05) diets. Fecal material (trial start, 36d, and 72d) was collected for an assessment of the intestinal microbiota via 16S sequencing (V3 and V4 regions) . Results indicate a difference in observed amplicon sequence variants (ASVs) across dietary treatments (P=0.030) and trial sampling timepoints (P=0.013), with the DDGS shifting constituents from 36d (17.9) to 72d ( 66.1; P=0.039). With respect to alpha diversity analyses, the REF diet display ed an increase in the Shannon i ndex over time (P= 0.031) and was found to be greater than the SBM group at 72d (P= 0.034). The results from this feeding trial will be of interest to commercial coldwater aquaculture producers, as this study better defines a satiation feeding schedule for burbot and demonstrates the potential of incorporating plant-based protein ingredients into future burbot diet formulations.