Morphometric analysis, which involves the quantitative assessment of biological forms and structures, has been widely employed in ecological studies to evaluate the influence of various environmental and biological stressors on organism morphology to understand fish growth, development, variation and population dynamics. In this study, 405 Clarias gariepinus consisting 204 males (50.4%) and 201 females (49.6%) were examined in Ibadan, Southwest Nigeria, using both linear and weighty measurements. The mean body weight (MBW) of pooled population was 414.70±8.97g, while both the mean standard length (MSL) and total length (MTL) were 37.82± 0.22cm and 32.87±0.19cm respectively. The mean values of other parameters were those of intestinal length (MIL; 35.53±0.54cm), intestinal weight (MIW;14.0±0.41g), gill weight (MGW; 18.30±0.35g), head length (MHL; 10.15±0.06), head breadth (MHB;7.70±0.09) and liver weight (MLW; 5.91± 0.17). Significant differences (p<0.05) were observed among the relationships of MTL-MSL, MSL-MIL, and MTL-MIL. Although, males exhibited generally higher morphometric values than female, except mean liver weight that show a statistically significant difference between sexes (p<0.05). In males, both MTL and MSL exceeded MIL, whereas in females, MIL was greater than MSL, with both showing significant difference (p<0.05). Strong positive correlation existed among MBW-MSL; MTL-MIW and MGW- MHL, while weak correlations occurred in MBW-MIL; MBW-MHB; MSL-MIL; MIL-MHB in the entirety of the fish population. Sex based variation in morphometric relationships may likely reflect factors such as diet, habitat, trophic level, physiology and environmental conditions. In overall, the observed morphometric correlations among various organs in this study may indicate an innocuous environment and its suitability for fish culture. However, further studies incorporating both biotic and abiotic influences on fish morphometrics are recommended.