THE SURVIVAL RATE AND RESPIRATORY BURST ACTIVITY OF CATFISH Clarias sp. USING MICROENCAPSULATED PROBIOTIC AGAINST MOTILE AEROMONADS SEPTICEMIA DISEASE  

Motile Aeromonads Septicemia disease outbreaks are being increasingly recognized as a significant constraint on freshwater aquaculture production. To avoid this disease, the prevention and control is very crucial. There is a growing concern about the use and particularly abuse of antimicrobial drugs not only in human medicine and agriculture but also in aquaculture.

An alternative to prevent and control pathogenic bacteria is the use of probiotics to improve resistance to disease and/or growth of farmed fish and water quality. On the basis of three working models of probiotic that is, the reduced population of microbes through competition by producing anti-microbial compounds or through competition from nutritional and place attachment in the intestinal wall, altering the balance of microbial metabolism by increasing and decreasing the activity of enzymes and stimulates immunity by increasing antibody and macrophage activity. Probiotic encapsulation process with maltodextrin and whey in this research using a minispray dryer within let temperature of 131-133°C and outlet temperature of 65-70°C to enhance  the quality of probiotic via per oral. The aim of this research to know the immunostimulatory activity and cell viability of encapsulated probiotic that it will be observed once every 3 days for 30 days by way of plating. The result showed that microencapsulated probiotic ND2 and L1K using 2% dosis and giving every two days for one month can improved the immune response respiratory burst activity and survival rate 20% respectively compared with non microencapsulated probiotic and control.