In cooperation with the WAS Employment Service

Michael Gotesman


Email Address: mgotesman@brooklyn.cuny.edu
Address: 965 52nd st 2
City: Brooklyn
State/Providence: NY
Zip Code: 11219
Country: United States
Phone Number: 6468067785
Date Posted: 2/3/2017

Objective

My objective is to find a Research Scientist, or related position.

Education

EDUCATION The Graduate Center, City University of New York (CUNY), Brooklyn, NY PhD, September 2006 - May 2011 Biology: Myosins, Tetrahymena thermophila, Intracellular Trafficking Advisor: Professor R.H. Gavin Brooklyn College, City University of New York (CUNY), Brooklyn, NY Bachelors of Science degree with honors and distinction, June 2001- May 2005 Major: Biology, Minor: Chemistry. Honors: ASCB Travel Award; 2010, Brooklyn College Doctoral Fellowship; Fall 2010, CUNY Science Fellowship; 2006-2011, Janet Horowitz Hecht Memorial Biology Award; 2005-2006, Jeanette Trum Granoff’ 35 Graduate Award for Applied Sciences; 2005-2006. Dean’s List, fall 2004, fall 2002, spring 2002, fall 2001. TRAINING COURSES University of Veterinary Medicine, Vienna, Posdoc Retreat, Neusiedl/See, Austria, 2012 Pan American Studies Institute (PASI), Function and Regulation of the Cytoskeleton, Rio de Janerio, Brazil, 2010.

Experience

My previous project at the Technion involved the use of florescence microscopy to monitor the cellular processes related to dormancy in the Monogonont Rotifer, Brachionus plicatilis Müller. During the investigation, encysted resting eggs were stained with Hoechst dye, to monitor nuclear development for eggs that were collected at sequential time points after fertilization. A preliminary manuscript based on the methods employed in this investigation have been accepted in the Annals of Clinical Laboratory Research and a report based on findings of this investigation is being developed into a manuscript. My project at the University of Florida involved characterizing a group of aquatic viruses in the family Iridoviridae, which infect both freshwater and marine fish. Many of the susceptible fish are economically important for food or ornamental purposes. The ultimate goal of this research was to create detection and control strategies to limit the detrimental effects of this family of viruses. A manuscript based on that work has been accepted in the Journal of Fish Diseases, in addition to a book chapter. My project at the Veterinary Medicine University in Vienna, Austria, investigated the molecular interactions of two distinct fish viruses, termed Koi Herpesvirus (KHV) and Spring Viraemia of Carp Virus (SVCV) that infect carp and other Cyprinus fish. The focus of this project was to use small interfering RNA (siRNA), targeted against viral transcripts, to inhibit in vitro viral replication. Based on the of this investigation, two preliminary reports concerning the host-viral interactions of KHV in koi carp have been accepted as a manuscript in the Journal of Fish Diseases. Two additional reports regarding siRNA knockdown of KHV and SVCV have also been accepted in the Journal of Virological Methods and JFD, respectively. My PhD research investigated the function of two different tail domains in Myo1, a myosin in Tetrahymena thermophila. During the project, varying GFP-tagged truncated regions of the Myo1 tail domain were expressed in Tetrahymena. That research showed that although the domains share overlapping biochemical properties, the domains localize to discreet regions of Tetrahymena and cause different phenotypes when overexpressed. The aforementioned research was developed into two publications in Cytoskeleton.

Publications

Gotesman M, Dahan N. A Simple Method for the Decapsulation of Dormant Resting Eggs for Nuclear Staining in the Monogonont Rotifer, Brachionus plicatilis Müller. 2016. Annals of Clinical Laboratory Research, 4:70 Subramaniam, K, Gotesman, M, Smith, CE, Steckler, NK, Kelley, KL, Groff, JM, Waltzek, TB. 2016. Megalocytivirus infection in cultured Nile tilapia Oreochromis niloticus. Diseases of aquatic organisms, 119: 253-258. Gotesman M, Menanteau-Ledouble S, El-Matbouli. 2016. Proteomic Analysis of Cytoskeleton Proteins in Fish. Cytoskeleton Methods and Protocols: Methods and Protocols, 357-372. Gotesman M, Williams SA. 2016. Using a Hand-Held Gene Gun for Genetic Transformation of Tetrahymena thermophila. Cytoskeleton Methods and Protocols: Methods and Protocols, 373-383. Kumar G, Gotesman M, Abd-Elfattah A, El-Matbouli. 2015. Investigating the interactions of Tetracapsuloides bryosalmonae (Myxozoa) with host proteins in kidney of brown trout Salmo trutta. Parasitology Research 114: 1721–1727. Amanda L, Duffus J, Waltzek TB, Gotesman M, Marschang RE, Allender MC, Stöhr A, Whittington R, Hick P, Hines M. 2015. Distribution and biology of fish ranaviruses Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates Ed. M.J. Gray & VG Chinchar. New York, pp 9-57. Springer Press Llc. Gotesman M, Soliman H, Besch R, El-Matbouli. 2014. Short Communication - In Vitro Inhibition of Cyprinid Herpesvirus-3 Replication by RNAi. Journal of Virological Methods 206: 63–66. Langenmayer MC, Lewisch E, Gotesman M, Hoedt W, Schneider M, El-Matbouli M, Hermanns W. 2015. Short Communication - Cutaneous infection with Dermocystidium salmonis in cardinal tetra, Paracheidoron axelrodi (Schultz, 1956) Journal of Fish Diseases 38: 503–506. Gotesman M, Soliman H, Besch R, El-Matbouli.2015. Inhibition of Spring Viraemia of Carp Virus replication in an epithelioma papulosum cyprini cell line by RNAi. Journal of Fish Diseases 38: 197-207. Gotesman M, Soliman H, Abd-Elfattah A, Kattlun J, El-Matbouli. 2014. Short Communication - Investigating the interactions of CyHV-3 with host proteins in goldfish Carassius auratus. Journal of Fish Diseases 37: 835-841. Gotesman M, Kattlun J, Bergmann SM, El-Matbouli. 2013. Review, CyHV-3: The Third Cyprinid Herpesvirus. Diseases of Aquatic Organisms 105: 161-174. Kattlun J, Gotesman M, Bergmann SM, El-Matbouli M. 2013. Die Erkrankung der Karpfen (Cyprinus carpio) mit dem Cypriniden Herpesvirus 3 (CyHV-3) – ein Update/ Infection of carp (Cyprinus carpio) with Cyprinid Herpesvirus 3 (CyHV-3)-an update. Wiener Tierärztliche Monatsschrift – Veterinary Medicine Austria 100: 72-84. Gotesman M, Soliman H, El-Matbouli. 2013. Antibody screening identifies 78 putative host proteins involved in Cyprinid herpesvirus-3 infection or propagation in common carp Cyprinus carpio L. Journal of Fish Diseases 36: 721-733. Gotesman M, Williams SA, Garcés J, Gavin RH. 2013. "Chromosome Walking by Inverse PCR." PCR Technology: Current Innovations 3rd ed. Ed. T. Nolan. London, pp 299-305. CRC Press Llc. Gotesman M, Hosein RE, Gavin RH. 2011. MyTH4 and FERM have distinct roles that are essential for the function of a class XIV myosin in Tetrahymena thermophila. Cytoskeleton 68: 220–236. Gotesman M, Hosein RE, Gavin RH. 2010. A FERM domain in a class XIV myosin interacts with actin and tubulin and localizes to the cytoskeleton, phagosomes, and nucleus in Tetrahymena thermophila. Cytoskeleton 67: 90-10.

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