One of the areas of great interest to all countries in the Middle East and the Red Sea region is the development of additional food resources and the enforcement of food security. These goals can be partly attained by improving intensive farming technology, such as intensive aquaculture. Almost by definition, agriculture in this arid region has to be based on the use of as little freshwater as possible due to the limited rainfall at these latitudes. Marine aquaculture farming, or mariculture, offers an excellent solution as it is based exclusively on the use of seawater. All countries in the northern Red Sea area suffer from a deficit of seafood production and face poor fishing conditions. Jordan for example has been importing almost all of its seafood consumption (about 97%). Lately, concern has been raised regarding the effect of the fish cages on the Gulf of Aqaba fragile ecosystem. This results in an urgent need for development of alternative solutions. Land-based mariculture has the potential to provide an economic efficient and environmentally friendly food resource for all countries around the Red Sea using the technology of recirculating aquaculture systems (RAS). Such technology is advantageous in terms of its low environmental impact as up to 95% of the water is recycled. This enables lower water consumption and a more effective effluent treatment for reducing the nutrient load on the receiving water body. In environmentally sensitive areas such the Red Sea and more specifically in Jordan known for its extremely low nutrient concentrations supporting flourish coral reefs. We endeavor developing aquaculture that is consistent with the recent national regulations of which the removal of aquaculture wastes is a prerequisite to all future land aquaculture activities and development. Therefore, any water treatment solution will have to include a component addressing nitrogen as well as phosphate removal. Our primary goal toward enhancing the knowledge of environmentally friendly and economic-efficient intensive land-based marine aquaculture in Jordan was by the development of efficient and cost-effective treatment sequence for complete removal of soluble ammonia and nitrate from the effluents of intensive RAS. In addition, reduce seawater consumption in makeup water flow rate which might affect both cultured species (i.e. fish, shellfish) quality and growth parameters. Hence, the effects of operational parameters makeup water flow rates and recycling strategies was explored on cultured species growth as well as quality at low rearing water exchange rates. Using RAS in Jordan’s aquaculture practices is specifically calibrated for endemic cultured fish species. This technology actually paved the road for the use of RAS in supporting sustainable marine aquaculture in Jordan’s Red Sea. At the same time, avoiding direct exploitation of the limited coast and expanding in intensive land based rearing systems.