Snook is considered to be one of the most important fisheries in Mexico is considered one of the most important fish species because of its commercial and nutritional value. Blood biochemical parameters are frequently used to determine the health status of cultured fish. The objective of this study was to evaluate the metabolic variables of the white snook Centropomus viridis culture in 10m diameter and 3m deep cages (235m3), 60 (30 juveniles and 30 adults) organisms were stacked during the experiment. The physicochemical parameters such as dissolved oxygen, temperature, pH and salinity as well as ammonia, nitrites, nitrates and metabolic variables such as glucose, protein, lipids and cholesterol were closely monitored, and recorded. Performance variables such as specific growth rate, and survival were evaluated. The results of our performance variables were a daily growth rate of 2.17 ± .06, 2.35 ± .05 and 2.49 ± .06 g, and 1.67, a total survival of 27% for the nursery stage and 60% for the grow out stage; the metabolic variables the protein and cholesterol had significant differences. Correlation between physicochemical parameters and growth was determined through a correlation analysis and a direct correlation was found between temperature and growth.