One alternative for producing sustainable food is aquaponic, which by recirculating effluent from aquaculture and hydroponic systems generates more organic and efficient crops, since it reduces the production of polluting effluents to make a biorational use of resources used in farming techniques and traditional aquaculture. Saladette (Solanum lycopersicum Mill) and cherry (S. lycopersicum var cerasiforme.) and the production of tilapia (Oreochromis niloticus) in an aquaponic system from different concentrations of nitrate. In this study, the yield of two tomato materials in different concentrations of nitrate and the effect on tilapia growth were evaluated, with the purpose of finding a concentration to provide the best conditions for the survival and healthy development of both species. In a closed system the nitrate concentration was controlled by dilution, to obtain the concentration of each treatment. In tilapia growth 4 treatments were evaluated; (TSI: 350 mg/L, TSII: 150 mg/L, TCIII: 150 mg/L and TCIV: 150 mg/L) with 45 fish m3. In both studies growth variables (specific growth rate, SGR), food conversion efficiency (FCE) and survival (S%) were evaluated. In agricultural experiment were evaluated 6 treatments: Saladette (TS), TSI= 744 mg/L (control), TSII: 350 mg/L; TS III: 150 mg/L and Cherry TCIV: 744 mg/L (control), TCV: 350 mg/L and TCVI: 150 mg/L, and; were grown 3.6 plants/m, and physiological variables (fruit weight, height and thick of stem) and production total (TP) were evaluated. Between treatments of aquaculture no significant difference (p > 0.05) were obtained. The growth variables were recorded as follows: mean 0.7 g/day and and FCA 1.2 and 100% survival in all treatments. Physiochemical parameters (temperature, pH and OD), recorded values within appropriate for cultivation of O. niloticus limits. Tomato yield significant differences were observed in both main effects. In the agricultural cultivation the best production materials tomato was presented in Saladette with a value of 65.53 t/ha, and the reduction test of nitrate was obtained at the level of 350 mg/L NO3- with 57.73 t/ha.