Nowadays antibiotic resistance is one of the major concerns all over the world. Discovery of anti-bacterial agent from natural source is creating a new dimension to overcome antibiotic resistance problem. Sea urchin, a marine invertebrates of the Phylum Echinodermata, have lots of therapeutic activities. This study aims to determine the antibacterial activity of ethanol and ethyl acetate body wall extract of Arbacia punctulate and Strongylocentrotus droebachiensis. The body wall extracts of these two species of sea urchins were prepared by following a standard protocol. Then crude concentrated extracts were used against five gram-positive and five gram-negative pathogenic bacteria by disk diffusion method to observe the zone of inhibitions. Our study revealed that both ethanolic and ethyl acetate extracts of Arbacia punctulate and Strongylocentrotus droebachiensis have potential antibacterial activitis against pathogenic bacteria. Moreover ethyl acetate body wall extract of both sea urchins species showed significant inhibitory activity against all the bacterial species (five gram-positive and five gram-negative) used for this experiment. Detailed observation and statistical significance will be presented at the conference.
Keywords: Sea urchins, body wall extract, Arbacia punctulate, Strongylocentrotus droebachiensis, antibacterial activity,