Carangid marine fish species within the genus Seriola have been cultured on a commercial scale for nearly 75 years globally and are highly regarded by consumers and culinary professionals. Multiple species within this complex of yellowtail jacks have been identified as promising aquaculture candidates for further development in various regions and types of production systems. While much of the global Seriola production has historically utilized wild-caught juvenile seedstock for growout operations, there have been significant advances in hatchery technology of multiple Seriola species to allow for increased levels of closed-cycle production where fish are produced from eggs of captive broodstock. Each species of Seriola has its own unique life history, including specific thermal niches, energetic requirements, spawning dynamics, and larval rearing requirements. The differences extend to the marketplace, where species of Seriola, sizes of fish, specific preparations, and end-use markets all serve to impact the overall farm-gate price of harvested Seriola. Through combined analysis of all such factors, from biological to market-based considerations, the overall aquaculture performance potential of species can be assessed. Comparative analysis of the aquaculture performance dynamics of Seriola species reveals a multitude of key advancements in this industry while also highlighting critical challenges that remain within this sector of global marine aquaculture. Aspects of Seriola species-specific differences will be presented and discussed, including analysis of recent advances in comparative bioenergetics research and overall aquaculture performance potential of Seriola spp. throughout the world.