Antimicrobial resistance (AMR) is an increasing threat globally in public health and animal health care. Emergence and dissemination of multidrug resistant bacteria resulting from overuse or abuse of antimicrobial drugs makes this situation critical. With the increased interest in intensive aquaculture to meet the needs for protein consumption for the growing global population, assessing the role of aquaculture in AMR dissemination is of paramount importance.
The minimum inhibitory concentration (MIC) assay is performed using microbroth dilution to measure, under defined test conditions, the lowest effective concentration of an antimicrobial agent that inhibits the visible growth of a bacterium of interest. Antimicrobial susceptibility testing of clinical isolates from sick aquaculture animals aid in understanding the prevalence, prediction and management of drug resistant bacteria in farming practices
Antibacterial properties of compound were assessed by microbroth dilution method using a range of concentrations 0 – 1024 µg/ mL against gram negative and gram positive bacteria viz. Vibrio parahaemolyticus and Streptococcus iniae.