India is the world’s second-largest producer and exporter of farmed shrimp, yet the environmental performance of its farms remains poorly understood. Production practices and input use differ markedly across regions, but how these regional variations influence sustainability outcomes has not been systematically assessed. This study asks whether regional production contexts in India shape the environmental performance of shrimp aquaculture, and identifies the key input and management factors driving these differences. W e use life cycle assessement (LCA) method to assess regional differences in shrimp farming across three major producing states on India’s east coast , namely Tamil Nadu, Andhra Pradesh, and West Bengal, drawing on detailed farm-level data from 45 commercial operations, of which 24 (eight per state) were selected for systematic analysis. We developed a stoichiometric nutrient model to estimate nitrogen and phosphorus emissions, and constructed life cycle inventories using primary datasets supplemented with state-level proxy data. Environmental impacts were quantified using LCA-ReCiPe midpoint indicators in SimaPro, and statistical tests were applied to compare impacts across two perspectives: geographical clusters (states) and technical clusters (defined by days of culture and productivity). Results reveal clear regional heterogeneity. Inventories differed significantly across states in categories such as land use, electricity demand for aeration, operational hours of pumps and aerators, and dead shrimp disposal. At the impact assessment stage, 13 of 15 midpoint categories exhibited statistically significant state-level differences, as of the case of Global warming (kg CO2 eq) shown in Fig 1(A). In contrast, technical clustering showed limited variation, with marine eutrophication as the only category significantly affected (Fig 1.B). Hotspot analysis further indicated that electricity use, not feed, was the dominant driver of environmental impacts, challenging the prevailing assumption that feed is the universal hotspot in aquaculture systems. Our findings demonstrate that shrimp farming in India cannot be treated as environmentally homogeneous, as sustainability outcomes depend strongly on regional production contexts. These results highlight the need for region-specific strategies, including targeted energy management, improved waste handling, and locally tailored best practices, to reduce the environmental footprint of India’s most valuable aquaculture sector.