World Aquaculture 2025 India

November 10 - 13, 2025

Hyderabad, India

Add To Calendar 12/11/2025 12:20:0012/11/2025 12:40:00Asia/KolkataWorld Aquaculture 2025, IndiaDIETARY INACTIVATE YEAST Pichia guilliermondii PROMOTES SHRIMP GROWTH AND IMMUNITYHall 5The World Aquaculture Societyjohnc@was.orgfalseDD/MM/YYYYanrl65yqlzh3g1q0dme13067

DIETARY INACTIVATE YEAST Pichia guilliermondii PROMOTES SHRIMP GROWTH AND IMMUNITY

François Jégou*, francois.jegou@adm.com



Environmental and infectious stressors are ubiquitous in aquaculture. Achieving efficient and profitable production, especially with the increasing global threat on antimicrobial resistance, is critical for producers. Helping aquaculture species to better perform under multiple physiological  and infectious stressors is therefore of high interest and a focus of intensive research.

Cardozo et al., 20181 compared in vitro bacterial aggregation capacity of inactivated Pichia guilliermondii (Pg) with Saccharomyces cerevisiae (Sc), taking Mannose as Control. Pg showed twice aggregation capacity at all commercial  dosages compared to that of Sc (Fig 1). Bacteria aggregation is critical in first innate immunity, thus resilience and performance.

Environmental and infectious stressors are ubiquitous in aquaculture. Achieving efficient and profitable production, especially with the increasing global threat on antimicrobial resistance, is critical for producers. Helping aquaculture species to better perform under multiple physiological  and infectious stressors is therefore of high interest and a focus of intensive research.

Granular Hemocyte Count

To assess bacterial aggregation capacity and immune potent activity of Pg, a bacterial clearance study was performed: Litopenaeus vannamei shrimp were injected (IM) with Vibrio harveyi.  Three hours post-injection, V. harveyi concentration in the hemolymph of 4 weeks Pg fed shrimp was found to be reduced by 69% compared to control-fed shrimp (Fig 2). It was also shown that hemolymph granular hemocyte concentration was 56% higher compared to control3 (Fig 3). Granular hemocytes are key for an effective, rapid, and orchestrated immune response in shrimp.

In order to confirm the potential benefit of Pg in various shrimp culture conditions, challenge tests and growth studies were performed in  L. vannamei shrimp supplemented with 0.1% Pichia guilliermondii feed additive2 : Survivability of shrimp 5 weeks after White Spot Syndrome Virus challenge increased by 84% compared to non-supplemented Control shrimp, and was 76% higher 5 weeks post-Vibrio parahaemolyticus (VpAHPND) challenge vs Control3.

Interestingly, significant 10% higher growth performance were shown compared to control on shrimp fed with the same supplementation during 7 weeks in common field conditions3.

To conclude, inactivate whole yeast Pichia guilliermondii feed supplementation offers unique benefits to shrimp culture and daily management, significantly improving growth as well as helping shrimp to better cope with physiological and infectious stressors.

* Archer Daniels Midland (ADM) ;  1 Cardozo P, Calvo Torras M, Less J, et al. The aggregation capacity of oligosaccharides from different yeast preparations to bind different pathogenic bacteria. Journal of Animal Science 2018; 96:304; 2AquaTrax, whole-cell inactivated yeast Pichia guilliermondii, ADM; 3All sources are available upon demand.

The uses and claims should be adapted to comply to the current local/ regional regulatory environment. This information does not imply any express recommendations for the cure, mitigation, treatment, or prevention of diseases.